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rheumatology differential syndrome activation approach arteritis bloodcell dermatology disease druginduced gca giantcell joint laboratory lupus macrophage mas microscopy msk nomenclature
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
joint trauma (e.g ... subchondral bone (e.g ... derangements (e.g ... #approach #workup ... #differential #diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... them, but urgent rheumatology ... #Management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... inflammatory disease (e.g ... Chemistry profile (e.g ... #laboratory #workup ... #diagnosis #testing
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... underlying disease (eg ... • Infection (eg ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... • Immunologic Workup ... druginduced #lupus #sle #comparison ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... • A clinical diagnosis ... antiinflammatory properties e.g ... #diagnosis #management ... #Dermatology
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