17 results
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
and laboratory diagnosis ... , not a morphologic ... count, D-dimer, egg ... hemolytic #anemia #Hematology ... #Pathology #Smear
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... not required in all ... #hematology
Anaplastic large cell lymphoma, ALK+
Clinical
 • First 3 decades of life, M>F
 • Often nodal +
cell lymphoma, ALK ... sometimes fried-egg ... morphology, but ... than one • Rare cases ... ALKPos #hemepath #pathology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
Bell's Palsy - Diagnosis ... ) • LP (if suspect ... CNS inflammatory cause ... ) • EMG/NCS (rare ... within 4m #Bells
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... lateral sclerosis Pathophysiology ... - Causes progressive ... EMG: LMN Signs in ... Lateral #Sclerosis #neurology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Auto-amplification loop Diagnosis ... Griscelli, Purtilo (XLP ... Drugs, Unknown cause ... treatment #summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... Inability to produce all ... classes of immunoglobulin ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Lysis of tumor cells ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology