8 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... #diagnosis #management ... #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... lateral sclerosis Pathophysiology ... - Causes progressive ... EMG: LMN Signs in ... Lateral #Sclerosis #neurology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... pain that worsens as ... identifies 85 to 95% of cases ... #Temporal #Signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... (for secondary APS ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
/Cranial nerve pathology ... Generalized fatigue - ALS ... Serologic and EMG ... - Peek sign ... #management #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... affects the skin, neurologic ... tract, and often causes ... aneurysms can also ... #Rheumatology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Mutism Pathophysiology ... horizontal movements; also ... • Examine for signs ... #PhysicalExam #neurology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
anemia (MAHA) Pathophysiology ... rule out other pathology ... • Refractory cases ... Renal #Crisis #rheumatology ... #nephrology #diagnosis