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rheumatology management differential erythematosus lupus sle treatment activation aspergillus bleeding cardiology causes cerebritis classification cns cryofibrinogenemia cryoglobulinemia cryoglobulins dermatology disorders
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
halt nail growth (e.g ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... permeability Diagnosis ... Lumbar Puncture, EEG
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... : • Clinical triad ... Labs/Diagnosis: ... tissue disorder (e.g ... . systemic lupus
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
immunosuppression (eg ... HIV/AIDS, CGD) Clinical ... sometimes have this morphology ... AmphoB or Vori + systemic ... treatment #fungal #infectiousdiseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... . hematologic) ... Clinical Features ... Erythematosus #Diagnosis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... processes: • Systemic ... : • + Clinical ... Antiphospholipid syndrome ... hematology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Hypercoagulable (APLAS ... Vascular: • Systemic ... Cholesterol emboli syndrome ... ↑ ESR, CRP • EKG ... #cardiology #infectiousdiseases
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... • Presence of systemic ... Marfan syndrome, ... peds #pediatrics #diagnosis ... #hematology #primarycare
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