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differential management joint arthritis gout activation approach autoimmune calcium comparison conditions deposition dermatology disease erythematosus extrarticular lupus macrophage mas monoarthritis
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
onset of swelling, pain ... concomitant infection ... • Metabolic syndrome ... concomitant infection ... Gout #Comparison #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint Pain ... Calcium oxalate Infectious ... Acute or chronic infections ... #MSK #rheumatology ... #differential #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... peripheral vs axial (spine ... - Autoimmune Rheumatologic ... #Differential #Diagnosis ... #MSK #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... skeleton-sacroiliac joint and spine ... causes such as infectious ... antiinflammatory properties e.g ... #Rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Fever is the main ... underlying disease (eg ... SLE], AOSD) • Infection ... #Diagnosis #Management ... #Hematology #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... disease, Vasculitis (e.g ... Cardiomyopathies - Viral infection ... #differential #diagnosis ... #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
onset of swelling, pain ... concomitant infection ... Crowned Dens Syndrome ... with acute neck pain ... Deposition #Disease #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... fibromyalgia) • Infections ... . hematologic) ... Arthritis: • Joint pain ... #Rheumatology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
sex • Metabolic syndrome ... swelling, significant pain ... concomitant infection ... Dual-energy CT → MSU ... management #treatment #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tenderness → Consider infectious ... Aldolase levels • EMG ... RP-ILD), dermato-rheumatologic ... forward of the spine ... Myositis #Myopathy #rheumatology
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