11 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... alone but typically ... Pre-analytical cause ... #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Prolonged PT and aPTT ... the PT and the aPTT ... #diagnosis #differential ... #hematology #coagulation
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... Platelet #Disorders #Differential ... #Workup #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
platelet, PT, PTT ... count and platelet morphology ... 1 or Type 3) — differentiate ... considered first-line ... #hemepath #differential
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Chemotherapy (e.g ... #differential # ... diagnosis #hematology ... #microscopy #atlas
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS ... Septic Emboli Cause ... Marantic (NTBE) Differential ... ↑ ESR, CRP • EKG ... Treat underlying cause
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... immunosuppression (eg ... Endophthalmitis, Endocarditis ... Non-pigmented (hyaline ... sometimes have this morphology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... weeks) Can Be Caused ... - Autoimmune Rheumatologic ... • Bacterial endocarditis ... #Joint #pain #Differential
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential ... Hypercoagulable (APLAS ... Septic emboli cause ... ↑ ESR, CRP • EKG ... #Differential #
Common Dermatological Conditions - Distribution and Morphology
 • Acne vulgaris - Face, upper back, chest -
Distribution and Morphology ... and pruritus (e.g ... honey-colored crusts ... Varies with site, (e.g ... dermatology #rash #differential