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differential management causes clinical physicalexam treatment weakness algorithm diplopia doublevision eyelid half manifestations multiple neuritis neuromuscular neuromyelitis ocular one oneandahalf
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Demyelinating Disease (MS ... Tetanus, Transverse Myelitis ... Eaton Syndrome, Myasthenia ... Gravis, Organophosphate ... #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis ... Diagnosis - ... - Peek sign ... #Gravis #diagnosis ... #management #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Sjögren syndrome, Myasthenia ... gravis, Many others ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Diplopia - Double Vision - Differential Diagnosis Algorithm Clinical Pearls: • Diplopia is almost always binocular. •
• Neurologic ... symptoms suggest ... • Myasthenia ... Neuromuscular Junction • Myasthenia ... Algorithm #Causes #Ophthalmology
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
Myasthenia gravis ... such as cogan sign ... #clinical #video ... #ophthalmology ... #neurology
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 Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis (MS ... nearly 3:1 • MS ... neuritis • Partial myelitis ... Signs and symptoms ... criteria for MS
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
- Differential Diagnosis ... Postsynaptic: Myasthenia ... Gravis - Lack ... of UMN/LMN signs ... #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... and/or symptoms ... swollen, while in MS ... Predictive of MS ... Multiple sclerosis (MS
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Optic Neuritis - Diagnosis ... caucasian • Symptoms ... Unilateral • Signs ... - Typical MS-like ... #rheumatology #ophthalmology
One and a Half Syndrome on Physical Exam This 28 year old patient presented to clinic with
eye is fixed (no ... the hospital, diagnosed ... with MS, and started ... #ophthalmology ... #neurology
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