17 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
These cells can ... Crises can be precipitated ... The underlying pathophysiology ... #Features #Signs ... #Symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
chromosome 21) Signs ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... and Symptoms • ... ), Increased blood ... formation, Genital atypia ... #endocrinology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... endothelium) & Decr blood ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... Tuberculosis: can ... be a clue • Blood ... addisons #disease #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... • Salt wasting crisis ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
10,000 ft) • Symptoms ... • Signs/Symptoms ... • Signs/Symptoms ... - The classic signs ... : - PE can cause
Avascular Necrosis: Pathogenesis and Clinical Findings
 • Physical Trauma (esp. to the scaphoid bone with damage
disease (sickle crisis ... ) • Multiple causes ... therapy - Lupus ... AvascularNecrosis #pathophysiology ... #symptoms
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... besides glucose that can ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... the seepage of blood ... Pathophysiology: ... the digestion of blood ... onset of other symptoms