11 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... #diagnosis #signs ... #symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... lumbar spine Signs ... Areflexia (loss of normal ... leg reflexes) ... #signs
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Unresponsive wakefulness syndrome ... • Locked-in syndrome ... decortication), abnormal ... • Examine for signs ... #PhysicalExam #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... bladder and rectal reflex ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Neuroleptic Malignant Syndrome - Diagnosis
Neuroleptic Malignant Syndrome is an idiosyncratic reaction to antipsychotic medications classically characterized
antipsychotic medications ... of dopaminergic medications ... status: catatonic signs ... , sialorrhea), Reflexes ... #Diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... injury • Gait is abnormal ... MCTD, Sjogren syndrome ... dysfunction • Abnormal ... reflexes: Areflexia
Newborn Infant - Routine Examination

Birthweight, gestational age and birthweight percentile are noted.
General observation Of the baby's
is also a late sign ... If abnormal, this ... This reflex is not ... are observed for signs ... Examination #Peds #Pediatrics
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
bilateral, malignant, pediatric ... and Signs: 50% ... and signs: • ... hypotension (may reflect ... or with certain drugs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
atherosclerotic disease, drug ... purpura: Strong sign ... • Progressive symptoms ... fluid (CSF) is abnormal ... viral infection, drug
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... Sjogren's • CSF: - Abnormal ... diagnosis #management #neurology