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Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
palpable versus nonpalpable ... Nonpalpable purpura ... presents in thrombocytopenic ... have idiopathic thrombocytopenic ... likely to have thrombocytopenia
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
Primary hemostasis: Thrombocytopenia ... BrighamChiefs #Purpura #nonpalpable
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
→ Palpable • Thrombocytopenia ... BrighamChiefs #Purpura #nonpalpable
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... Primary Causes: - Thrombocytopenia ... rheumatology #palpable #nonpalpable
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
non-blanching, nonpalpable ... individuals with thrombocytopenia ... Bruise #ecchymosis #thrombocytopenia
Management of Immune Thrombocytopenia (ITP) . 

#Idiopathic #Thrombocytopenic #Purpura #Immune #Thrombocytopenia #ITP #Management #Hematology
Management of Immune Thrombocytopenia ... #Idiopathic #Thrombocytopenic ... Purpura #Immune #Thrombocytopenia
Differential for the Child with Petechiae or Purpura
 - Non-thrombocytopenic
 - Thrombocytopenia

#Diagnosis #Peds #Pediatrics #Petechiae #Purpura
Purpura - Non-thrombocytopenic ... - Thrombocytopenia ... #Differential #Thrombocytopenia
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... indicates thrombotic thrombocytopenic ... How to approach thrombocytopenia ... Differential #Algorithm #Thrombocytopenia
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... of drug-induced thrombocytopenia ... resolution of thrombocytopenia ... with drug-induced thrombocytopenia ... having idiopathic thrombocytopenic
Thrombotic Thrombocytopenic Purpura (TTP) vs Disseminated Intravascular Coagulation (DIC)
#Diagnosis #TTP #DIC #Comparison #Table #Laboratory #Findings #RebelEM
Thrombotic Thrombocytopenic ... Findings #RebelEM #Thrombocytopenia