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diagnosis differential hematology dermatology arterial behcets classification cryofibrinogenemia disease embolism nonpalpable palpable pathophysiology pharmacology polychondritis purpura relapsing sapho sjogrens thrombosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... : • Behçet Syndrome ... ulcers, cutaneous, ocular ... • Cogan Syndrome ... differential #diagnosis #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... considered in all cases ... coagulation and other causes ... - Vasculitis ... pathophysiology #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
tract, and often causes ... • Behcet syndrome ... • Cogan syndrome ... : Ocular inflammatory ... Differential #Diagnosis #Rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... refractory lesions Ocular ... by case) • Surgery ... #Treatment #management ... #pharmacology #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... pulmonary emboli, and ocular ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... #Rheumatology # ... Diagnosis #Management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... Rule out other causes ... sites such as the collar ... #Rheumatology # ... diagnosis #management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
chondritis • Ocular ... hearing loss, nausea ... diseases 30% of cases ... Polychondritis #rheumatology ... #diagnosis #management
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