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Hypoxemia vs Hypoxia Hypoxemia - Partial pressure of arterial oxygen (PaO2) is below normal Hypoxia - Insufficient oxygen
hypoxia - Increased O2 ... unable to use O2 ... O2 delivery to tissues ... differential #diagnosis #comparison
Oxygen Delivery Devices 1. Flow is a variable describing the movement of a volume of gas over
Room air is 21% O2 ... device is 100% O2 ... air mixes with O2 ... Devices #Flow #Comparison
Low O2 saturation that does not respond to supplemental O2 - Key diagnostic feature (sat < 85%
Low O2 saturation ... to supplemental O2 ... a falsely low O2 ... true decrease in O2 ... impairment of O2
Causes of Generalized Hypoxia - Differential Diagnosis • Hypoxemic - Not enough O2 (Most Common) •
Hypoxemic - Not enough O2 ... Cells can't use O2
Oxygen-Hemoglobin Dissociation Curve Left Shift (↓ O2 unloading to tissue), Left = Lower: • ↓ H+ (↑
Left Shift (↓ O2 ... Right Shift (↑O2
Lactic Acidosis - Overview and Pathophysiology Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
TYPE A: Impaired O2 ... ) • Decreased O2 ... Delivery • Increased O2 ... TYPE B: Impaired O2
Medications for High-Altitude Sickness Acetazolarnide • Carbonic Anydrase Inhibitor Bicarb diuresis & metabolic Acidosis ->
Anti-emetic O2 ... pressure Hyperbaric O2
#oxygen #deliver #mask #hospital #nasal #cannula #venturi #mask #face #nonrebreather #o2
nonrebreather #o2
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
demand, decreased O2 ... SVR and altered O2 ... therefore inadequate O2 ... therefore inadequate O2 ... therefore inadequate O2
Normal Intracardiac Pressures and O2 Saturations by Chamber #Normal #Intracardiac #Pressures #Saturations #Chamber #Cardiology #Diagnosis #Laboratory #Wedge
Pressures and O2
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