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workup evaluation fuo hypercoagulable leukostasis lysis management origin perioperative preop preoperative risk stratification syndrome thromboembolism tls tumor unknown vte
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
thromboembolism → Cardiac ... rhythm monitoring, Echocardiogram ... CBC, aPTT, +/- CXR ... #diagnosis #algorithm ... #hematology #VTE
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... acid, Elevated Cr ... Syndrome #TLS #diagnosis ... #management #hematology
Possible Algorithm for Workup of Fever of Unknown Origin (FUO) Tier 1 Workup: • CBC, comprehensive metabolic
Possible Algorithm ... SPEP, ANA, anti-CCP ... • +/- ESR, +/- CRP ... Neuroimaging • Echocardiogram ... Origin #Workup #diagnosis
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
or family - Ever ... exam Determine Cardiac ... event, follow ACC algorithm ... postoperative cardiac ... stratification #diagnosis
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