3398 results
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
Targeted Temperature Management ... and Neurologic Outcome ... month neurologic outcome ... #Temperature #Management ... VisualAbstract #EBM
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
primary composite outcome ... hospitalization for the management ... dCHF #Cardiology #EBM
The HYPERION Trial - Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm - Visual Abstract

NEJM
Targeted Temperature Management ... favorable neurologic outcome ... VisualAbstract #EBM
Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients

CJASN May 2019, 14 (5)
Hypernatremia and Health Outcomes ... Correction #Nephrology #Management ... #EBM #VisualAbstract
Summary of meta-analysis of pharmacotherapy trials in BPD
https://www.cochrane.org/CD005652/BEHAV_psychological-therapies-borderline-personality-disorder
Meta-analyses of RCTs were undertaken for the following outcomes:
the following outcomes ... mental state outcomes ... Guideline for the Management ... 5.2 and 5.4 #EBM ... #Management #Pharmacology
ProCESS Investigator - A Randomized Trial of Protocol-Based Care for Early Septic Shock

N Engl J Med
did not improve outcomes ... VisualAbstract #Threshold #EBM ... #Management
Transfusion Strategies for Acute Upper GI Bleeding

Conclusion: As compared with a liberal transfusion strategy, a restrictive
significantly improved outcomes ... VisualAbstract #Threshold #EBM ... #Management
Central line myth #2: location, location, location 

By far the best data we have to guide
have to guide management ... For the primary outcome ... pubmed/26398070 #EBM
Sepsis - Interventions that do / do not improve outcomes
Do:
- Have high index of suspicion and
do not improve outcomes ... Interventions #Management ... Factors #Matter #EBM ... Effectiveness #Improve #Outcomes
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
and CKD EMPA-REG OUTCOME ... T2DM; first renal outcomes ... Dapagliflozin improved HF outcomes ... Empagliflozin improved HF outcomes ... SGLT2 #inhibitors #EBM