6 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... Pre-analytical cause ... #Prolonged #Causes ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the aPTT ... are both prolonged ... #Prolonged #Causes ... #differential #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
is prolonged, but ... mixing study (aPTT ... normal in mild cases ... hemophilia type (e.g ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... Treat primary cause ... INR < 2.3 - APTT ... #treatment #management ... #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Pustular skin lesions ... Rule out other causes ... and lower jaw Treatment ... antiinflammatory properties e.g ... diagnosis #management #Dermatology
Pyoderma Gangrenosum (PG)
50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
dysregulation➡️lesions ... Management of PG lesions ... corticosteroid (eg ... PG secondary treatment ... clinical #photo #dermatology