7 results
diagnosis differential abnormal intravascular prolonged pt treatment anemia bleeding blood bruising disseminated extravascular hemolysis hemolytic hemophilia hemostasis product reactions transfusions
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Treat primary cause ... INR < 2.3 - APTT ... #diagnosis #causes ... #treatment #management ... #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... (DIC) c. ... #differential #hematology ... #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... intravascularcoagulation (DIC ... #differential #hematology ... #coagulation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation ... (DIC) - HELLP ... Extravascular #Causes ... differential #diagnosis #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... hemophilia type (e.g ... #treatment #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... Warfarin • Acute DIC ... discern these causes ... disease • Acute DIC ... Differential #Diagnosis #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... pain, dark urine, DIC ... Causes purpura & ... Transfusions #diagnosis #management ... #hematology #reactions
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