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Nephron - Diuretic Sites of Action

Source Text: https://www.sciencedirect.com/book/9780323449427/critical-care-nephrology#book-info

#Nephron #Diuretics #Site #Action #Location #Nephrology #Pathophysiology #Pharmacology
Nephron - Diuretic ... Sites of Action ... #Site #Action # ... Location #Nephrology ... #Pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Hormones Acting ... Their Site of Action ... spironolactone) #Pathophysiology ... #Nephrology #Nephron ... #Locations #SiteOfAction
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... of Action Diuretics ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... resistance • Metabolic ... the Nonspecific Cation ... Postoperative abdominal distention ... #Nephrology #Pharmacology
Weaning from the Ventilator - Algorithm
Setting up for extubation success
 • Decrease demand — correct metabolic
demand — correct metabolic ... avoid gastric distension ... with sedation vacation ... Mg and PO4) • Diuresis
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... vomiting/ nasogastric suction ... Thiazide or loop diuretics ... after renal tubule diuretic ... Diagnosis #Causes #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Gap Metabolic Acidosis ... Potassium-sparing diuretics ... Cation exchange ... aniongap #NonGap #Metabolic ... diagnosis #causes #nephrology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... OA in atypical locations ... A reaction to phagocytosed ... • Male sex • Metabolic ... • Medications (diuretics