5 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... #neurology #rheumatology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Pathophysiology ... diaphoresis, high HR ... unit activity on EMG ... of diazepam • EMG ... Management #treatment #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
• ESR > 50mm/hr ... affects the skin, neurologic ... cognitive impairment, neurologic ... chorioretinitis, CNS ... Differential #Diagnosis #Rheumatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
TAFRO TAFRO syndrome ... cirrhosis - TTP/HUS ... cell lymphoma Pathophysiology ... histopathologic changes in LNs ... diagnosis #management #rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... antigen assay has ... especially the CNS ... MC: CNS CSF: • ... Aspergillosis Pathophysiology