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diagnosis hepatology ascites differential management acutephasereactants bacterial gastroenterology gradient laboratory liver pathophysiology peritonitis prophylaxis spontaneous summary synthesis synthesized treatment
Ascites - Differential Diagnosis and Workup Algorithm • Perform paracentesis: • Cell count and diff • Total
Diagnosis and Workup Algorithm ... • Perform paracentesis ... protein • Fluid albumin ... and serum albumin ... • Calculate SAAG
Ascites - Diagnosis and Management Summary Paracentesis studies: cell count + differential, albumin, protein, culture • Serum-ascites-albumin-gradient
(SAAG): > 1.1 g ... hypertensive source • SBP ... suggests higher SBP ... Summary #Hepatology #SAAG ... #paracentesis
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
serum ascites albumin ... gradient (SAAG) ... SAAG ≥ 1.1: ... #ascites #albumin ... differential #diagnosis #algorithm
Spontaneous Bacterial Peritonitis DIAGNOSTICS Paracentesis: • Calculate absolute PMN count (total WBC x PMN %) • Correct
DIAGNOSTICS Paracentesis ... as 10 days 2) Albumin ... 1.5 g/kg of 25% albumin ... : lg/kg of 25% albumin ... Day 3 repeat paracentesis
Acute-phase Reactants Synthesized in the Liver Positive acute-phase reactants (concentrations increase with acute inflammation) - Immune-related
Serum amyloid A (SAA ... Lipopolysaccharide-binding protein (LBP ... Retinol-binding protein (RBP ... Transthyretin (TBPA) - Albumin
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