10 results
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... antigen-antibody complexes ... self-antigens are the cause ... antigens are the cause ... Allergy #Immunology #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
table of types of hypersensitivity ... Allergen-specific lgE causes ... Antigen-antibody complex ... Antigen-antibody complexes ... allergy #table #classification
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Manifestations • Immune Complex ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... Antigen-antibody complexes ... sclerosis #Hypersensitivity ... #Types #Classification ... #Pathophysiology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity ... cell surfaces causes ... antigen-surface complex ... #Hypersensitivity ... Reactions #Types #Classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... • They can cause ... Cryoglobulins Cause ... vasculitis • Hypersensitivity ... diagnosis #types #classification
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
nonimmune hemolysis MSK ... , or any other cause ... Meningococcemia • Hypersensitivity ... weeks #Scurvy #Pathophysiology ... #AscorbicAcid #Pathophysiology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... 10-33% develop MS ... monophasic Pathophysiology ... • Infectious causes ... virus - Herpes simplex
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Clinical Findings Classification ... • Complete isolated ... #PCL #Injury #MSK ... #Sports #pathophysiology ... #classification
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Osteoclast-osteoblast coupled ... Fluoroquinolones - Causes ... #Orthopedics #msk ... #Staging #pathophysiology