11 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... peanuts), Hay fever ... , Urticaria, Allergic ... Antigen-Ab immune complexes ... #Types #Classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
cell surfaces causes ... antigen-surface complex ... antibody-antigen complexes ... causes development ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... Anaphylaxis, Hay fever ... Antigen-antibody complex ... Antigen-antibody complexes ... #table #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... , seasonal hay fever ... Antigen-antibody complexes ... Hypersensitivity #Types #Classification
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
pyelonephritis Most common cause ... uncharacterized fevers ... (particularly complex ... Diagnosis #Peds #EM #Classification ... #Fever #SBI #SeriousBacterialIllness
Complex Ascites on POCUS
62 yo F with rec dx colon CA s/p colectomy, liver cirrhosis w
Complex Ascites ... diagnostic and tx paracentesis ... weeks ago, no fevers ... pocket for dx + tx paracentesis ... PittIMPOCUS #Complex
Modified dengue severity classification, PAHO/WHO
Dengue without warning signs - DNWS:
 • Person who lives or has
dengue severity classification ... days and presents fever ... and no apparent focus ... organs #dengue #fever ... #severity #classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Causes of Lactate ... The most common causes ... / hypoxemia -> focus ... the patient’s complete ... #typea #typeb #classification
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacterium tuberculosis complex ... status NTM Cause ... Growers (Runyon Classification ... Growers (Runyon Classification ... Avium Complex (MAC
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tracts Immune Complex ... tract, and often causes ... Coronary arteries - Fever ... Vasculitis: • Fevers ... #rheumatology #classification