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#paracetamol #paracetamoloverdose #NAC
#paracetamol #paracetamoloverdose ... #NAC
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
N-Acetyl Cysteine (NAC ... NAC helps replenish ... Figure 2.1 NAC has ... GSH) precursor, NAC3 ... substitute, and NAC4
Thiazide diuretics Carbonic anhydrase inhibitors (e.g., acetazolamide) Nat-Cl symport Na and HCO;- reabsorption Aldosterone antagonists (e.g., spironolactone) Nat channel (indirect effect) Loop diuretics (e.g., furosemide) Amiloride, #triamterene Nat-K+-2CF symport Na channel (direct effect) #NaCI reabsorption
acetazolamide) Nat-Cl ... symport Na and ... spironolactone) Nat ... +-2CF symport Na ... direct effect) #NaCI
Diuretic Electrolyte Excretion Effects Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid - Thiazide Type
Effects Diuresis, Na ... #pharmacology #comparison
5-Oxoprolinuria What is it: • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle • Amino acid transport and
Link to chronic paracetamol ... • Continuous paracetamol ... Diagnosis: • HAGMA; Paracetamol ... HDU • Withdraw paracetamol
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
Enterocolitis (NEC ... • Neutropenia (ANC ... 1min_idconsult #NEC
Warfarin and DOAC Pharmacology Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban Target - Prodrug - Bioavailability
#Pharmacology #NOAC ... #comparison #table
IV Fluids - Comparison Table Fluid - pH - Osm - Na - Cl - Other •
IV Fluids - Comparison ... Fluid - pH - Osm - Na ... #Fluids #IVF #Comparison
Antiarrhythmics - Sodium Channel Blockers Subclasses, Mechanisms, Indications, Side Effects la - Quinidine, Procainamide lb - Lidocaine, Mexiletine Ic -
Blockers #ClassI #Na ... pharmacology #table #comparison
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Decreased ENaC ... Beta-Blockers Decreased Na
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