8 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... phenomenon, SjS, cancer ... - SLE, SjS, RA ... #differential #diagnosis ... #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Symptoms: • Asymptomatic ... associated with autoimmune ... Biopsy: Typical pathologic ... #diagnosis #rheumatology ... #hematology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANAAutoimmune ... context of other symptoms ... : The ANA patterns ... , Interstitial Pulmonary ... #patterns #rheumatology
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Associated Features: Cancer-associated ... heliotrope, shawl sign ... exclusion Necrotizing Autoimmune ... : Proximal and distal ... #comparison #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... weeks) Can Be Caused ... Symmetrical: • RA ... #MSK #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA ... ab • RF • Antinuclear ... , INC risk PE, Pulmonary ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... Presentation - Systemic Symptoms ... purpura: strong sign ... ) pattern: antibodies ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
• Anti-TIF1 (cancer-associated ... Gottron sign) ... pattern of muscle ... statins - probably caused ... Myositis #Myopathy #rheumatology