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diagnosis classification antinuclear autoantibodies cryoglobulinemia cryoglobulins dermatology erythematosus lupus management myopathy myositis patterns prs pulmonary renal skin sle syndromes systemic
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... ANA - Non-specific ... c-ANCA - Vasculitis ... Microscopic polyangiitis ... #table #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
the Skin - Differential ... • ANCA Associated ... : - Microscopic ... : • Behcet Disease ... #dermatology #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
): • Microscopic ... mucositis - Rash ... LFT • ESR • ANA ... Dx: GPA, EGPA, microscopic ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(ANA) ANA or Anti-NucIear ... Using fluorescence microscopy ... Positive ANA ≠ Autoimmune ... #rheumatology #diagnosis ... #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... permanent alopecia Differential ... rheumatologic diseases ... • (-) ANA + (+ ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... , mucositis • Rash ... )): Microscopic ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... Henoch-Schönlein purpura) • Cutaneous ... classification #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
OnePager Summary Autoimmune ... ANCA vasculitis ... polyangiitis), MPA (microscopic ... : ANCA antibody, ... FINDINGS: • U/A: microscopic
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
• Anti-NXP2 (ANA ... Symptoms: • Gottron rash ... (ANA present 80% ... or head drop • ANA ... Myositis #Myopathy #rheumatology
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