6 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Microscopic polyangiitis ... Jcortesizaguirr #ANA ... #ANCA #Antineutrophil ... antibodies #diagnosis #rheumatology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pauci-Immune: - ANCA-positive ... , Microscopic polyangiitis ... ) - ANCA-negative ... testing: anti-ANCA ... , anti-GBM ab, ANA
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
small vessels - ANCA-associated ... - microscopic ... polyangiitis ... - systemic lupus ... Vessels #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
): • Microscopic ... Polyangiitis: ... Vasculitis: + MPO-ANCA ... Dx: GPA, EGPA, microscopic ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
: ANCA Associated ... Pauci Immune (ANCA ... )): Microscopic ... No Granulomas (ANCA ... #Rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... polyangiitis ... (e.g. systemic lupus ... classification #rheumatology