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diagnosis classification differential antibodies autoantibodies cryoglobulinemia cryoglobulins disease erythematosus laboratory patterns sle systemic testing types vasculitides vessels workup
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
hepatitis Anti-CCP, Rheumatoid ... c-ANCA - Vasculitis ... granulomatosis p-ANCA ... Microscopic polyangiitis ... #table #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Using fluorescence microscopy ... Rheumatic Diseases ... • Rheumatic Diseases ... • Non-Rheumatic ... #patterns #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
): • Microscopic ... Diagnosis: Systemic rheumatic ... LFT • ESR • ANA ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
small vessels - ANCA-associated ... granulomatosis - microscopic ... - systemic lupus ... dermatomyositis #Size ... Vessels #Diagnosis #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... polarized light microscopy ... ACE level, CXR, ANCA ... #Disease #Rheumatoid ... diagnosis #testing #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
respectively, having rheumatoid ... Elevated serum rheumatoid ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... classification #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic rheumatic ... : ANCA Associated ... Pauci Immune (ANCA ... )): Microscopic ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... Diagnosis: • ANCA-associated ... vasculitis, rheumatoid ... antibodies • (-) ANA ... Erythematosus #Diagnosis #Rheumatology
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