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anemia aplastic apml behcet cll common cryofibrinogenemia cvid disease hypogammaglobulinemia immunodeficiency immunology leukemia lymphocytic mds myelodysplasia myelodysplastic sapho variable workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Syndrome in APML ... : >3 symptoms, or ... #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... SAPHO syndrome is ... #Rheumatology # ... diagnosis #management ... #Dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... tests in Behcet syndrome ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... just beneath the skin ... Marrow Failure • Chronic ... #diagnosis #hematology ... #oncology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... Biopsy: Typical pathologic ... Antiphospholipid syndrome ... #rheumatology # ... hematology
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