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diagnosis rheumatology algorithm alopecia anemia behcet cll cord dermatology disease gravis hair hairloss infections leukemia loss lymphocytic mds myasthenia mycobacteria
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Anemia Clinical ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Alopecia mucinosa, Aplasia ... , Loose anagen syndrome ... Examination: • Signs ... weight loss • Chronic ... Dermatitis (Consider HIV
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... just beneath the skin ... • Anemia • Aplastic ... Marrow Failure • Chronic ... #oncology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... and signs below ... , HIV, CMV, HTLV ... MCTD, Sjogren syndrome ... #diagnosis #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... occlusion, Budd-Chiari syndrome ... tests in Behcet syndrome ... adenopathy (PFAPA) syndrome ... #signs #symptoms
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
an autoimmune disorder ... thyroid, Sjogren syndrome ... “dropping head syndrome ... - Kearns-Sayre syndrome ... Eaton myasthenia syndrome
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Lady Windermere Syndrome ... : • Syndrome of ... Hematologic malignancy ... NTM #Infections #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... Mucocutaneous lymph node syndrome ... tract, and often causes ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
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