11 results
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
pt w pure red cell ... aplasia. ... #Parvovirus #Pathology ... #Smear #Microscopy ... #Hematology #Clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... and laboratory diagnosis ... #Pathology #Smear ... #Microscopy
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
occurs when the plasma ... #Clinical #Pathology ... #Blood #Smear # ... Microscopy #Rouleaux ... #Formation #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
C Clinical Presentation ... • Peripheral smear ... Lymphocytosis: Absolute blood ... aplasia • ITP ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... Causes • Anemia • Aplastic ... smear • Bone marrow ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... smear - RBC agglutination ... Mycoplasma, EBV, HIV ... sensitize red blood ... hemolytic #anemia #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
which can plug blood ... : • + Clinical ... Biopsy: Typical pathologic ... • TTP, HUS and HIT ... hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Anemia Clinical ... - HCV - HIV ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... • Peripheral smear ... #Coagulation #diagnosis ... #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... , B cells, and plasma ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... #Diagnosis #Management