10 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... granules, and Auer rods ... #APL #APML #Pathology ... #Hematology #Clinical ... #Smear
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
a bone marrow (BM ... peripheral blood smear ... #Clinical #Path ... BloodSmear #Blood #Smear ... #Microscopy #Auer
Auer Rods - Bone marrow aspiration revealed 5% blasts and 65% promyelocytes; many promyelocytes had prominent
Auer Rods - Bone ... #Clinical #Path ... #APL #AuerRods # ... AcutePromyelocyticLeukemia #Smear ... #Microscopy #NEJM
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
linear red "Auer rod ... acute myelogenous leukemia ... #Clinical #Path ... BloodSmear #Blood #Smear ... #Microscopy #Auer
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... • Cytopenia -> BM ... 50-60 • Auer Rods ... • Peripheral smear ... lymphoma #Leukemia
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
(AML). ... to medium size lymphoid ... Prolymphocytes #Smear ... #Peripheral #Pathology ... #Microscopy #Clinical
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
Leukemia/Lymphoblastic ... Lymphoma Clinical ... disease with limited BM ... lauraebrown #BCell ... #pathology #prognosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Immunosuppression (e.g., HIV), EBV ... Autoimmune diseases • Clinical ... involved) • No leukemic ... Noncontiguous spread • Clinical ... Malignancies (eg CML, ALL
Hepatosplenic T-cell lymphoma involving hepatic sinusoids.

HSTL also involves BM sinusoids and splenic red pulp cords and
lymphoma involving ... also involves BM ... in essentially all ... #Pathology #Microscopy ... #Oncology #Clinical
Anaplastic large cell lymphoma, ALK+
Clinical
 • First 3 decades of life, M>F
 • Often nodal +
lymphoma, ALK+ ... Clinical • First ... lungs, liver) • BM ... variant can have leukemic ... ALKPos #hemepath #pathology