Hepatosplenic T-cell lymphoma involving hepatic sinusoids. HSTL also involves BM sinusoids and splenic red pulp cords and sinuses in essentially all cases. Usually young males, TCR g/d+, CD4-, CD8-/+, TIA1+ Isochromosome 7q is present in most cases. Median survival <2 years. - Kyle Bradley, MD @KyleBradleyMD #Hepatosplenic #TCell #Lymphoma #HSTCL #Pathology #Microscopy #Oncology #Clinical
