27 results
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... #Acromegaly #Signs ... Symptoms #Diagnosis #Endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
and Management ... malignancy Pathophysiology ... or refractory cases ... #Endocrinology ... #Treatment #Pathophysiology
Normal (Negative) Babinski / Plantar Reflex

The plantar reflex is a reflex elicited when the sole of
plantar reflex causes ... response or Babinski sign ... Normal #Clinical #Video ... #Signs #PhysicalExam ... #pyramidal
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... - Giantism or acromegaly ... #FeedbackLoop #endocrinology ... #pathophysiology
Trousseau's Sign of Hypocalcemia on Physical Exam

Carpopedal spasm caused by ischemia induced by an inflated blood
Trousseau's Sign ... Carpopedal spasm caused ... #Trousseaus #Sign ... Hypocalcemia #clinical #video ... #endocrinology
The Chvostek sign (/ˈkvɒstɪk/) is a clinical sign of existing nerve hyperexcitability (tetany) seen in hypocalcemia.It
The Chvostek sign ... is a clinical sign ... hyperventilation, which causes ... #PhysicalExam #Video ... #Clinical #endocrinology
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... Passive neck flexion causes ... While the pathophysiology ... Video by Dr. ... Meningitis #Clinical #Video
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... renal bruit or signs ... Causes: • Vascular ... Vasculitis • Endocrinologic ... Cushing's syndrome, Acromegaly
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... Signs/Symptoms/Complications ... Abdominal pain, nausea ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology