10 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... membrane into the CNS ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Passive neck flexion causes ... While the pathophysiology ... flexion occurs as ... Video by Dr. ... #PhysicalExam #Pediatrics
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... lateral sclerosis Pathophysiology ... - Causes progressive ... Lateral #Sclerosis #neurology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Treat underlying cause ... restriction • All ... on using this as ... • Give 250 cc ... #hyponatremia #nephrology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... should be done in ALL ... intervention CMC
Tromner Sign on Physical Exam

The Trömner sign is commonly used as a clinical neurological examination for
Tromner Sign on ... or index finger causes ... flexion of all ... Reflex #clinical #Video ... #Neurology #physicalexam
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... tract, and often causes ... , Elevated AST ALT ... aneurysms can also ... chorioretinitis, CNS
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Mutism Pathophysiology ... horizontal movements; also ... stimulation to all ... • Examine for signs ... #PhysicalExam #neurology
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
positive Romberg sign ... neuron disease (ALS ... ) • Clues: Focal ... Differential #Evaluation #Geriatrics ... #Neurology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... • In all patients ... Presentation • Common Signs ... Pathophysiology ... of NK cells and CD8