17 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Auto-amplification loop Diagnosis ... #management #treatment ... #summary #rheumatology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile Infection ... (CDI) - Diagnosis ... and Management ... Perforation) Pathophysiology ... #diagnosis #management
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Summary Pathophysiology ... not feasible CMC ... Bullous #Pemphigoid #Diagnosis ... #Management #dermatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... counts may delay diagnosis ... #differential #diagnosis ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Hepatitis B - Diagnosis ... and Management ... with chronic HBV infections ... • Monitor: CBC ... #Hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
and Management ... skin necrosis (at injection ... ♀, ↑Age, ESRD Pathophysiology ... Management: • ... #Hematology #HemeOnc
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
present or signs of infection ... Pathophysiology: ... also important Management ... pyelonephritis CMC ... #management
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Growers (Runyon Classification ... Growers (Runyon Classification ... Advanced HIV (CD4 ... Hematologic malignancy ... Diagnosis Of NTM
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... Complications: 1) Infection ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... opacities • Diagnosis ... • Differential Diagnosis ... : Infection (sepsis ... #management #hematology