11 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... Lymphocytosis on CBC ... surface molecules: CD5 ... Neutropenia, anemia, thrombocytopenia ... workup #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... decreased PLT count: CBC ... not required in all ... or if a primary hematologic ... Causes #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... Vmphocytosis on routine CBC ... Complications: 1) Infection ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... skin necrosis (at injection ... ♀, ↑Age, ESRD Pathophysiology ... D/c all heparin ... #Treatment #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... lymphoma, B-cell ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... specifically immune thrombocytopenia ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile Infection ... and Management ... Perforation) Pathophysiology ... #1 nosocomial infection ... - produced by all
A cirrhosis tweetorial all about the platelet

Aims:
- Identify cirrhosis based on blood tests- 
- Understand why
cirrhosis tweetorial all ... @ebtapper #Thrombocytopenia ... Platelets #Cirrhosis #CBC ... #Tweetorial #Hepatology ... #Pathophysiology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... precursors" • Stab cell ... overlook severe infections ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... • Induce blast cell ... Differential Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology