13 results
Running out of Analgesia and Sedation Medications due to #COVID19?  Anand Swaminathan, MD has put
Medications due to #COVID19 ... #management #covid19 ... #treatment #sarscov2 ... sedative #analgesia #pharmacology ... #alternatives #
Paxlovid Drug-Drug Interactions
Before prescribing ritonavir-boosted nirmatrelvir (Paxlovid) for outpatient treatment of COVID-19, determine whether the patient
for outpatient treatment ... of COVID-19, determine ... Interactions #DDI #pharmacology ... #COVID19 #SARSCOV2 ... #COVID #outpatient
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS)
Clinical features
all: fever > 101.3 F
most: oxygen
Inflammatory Multisystem Syndrome ... #Inflammatory #Syndrome ... #PIMSTS #covid19 ... #sarscov2 #coronavirus ... #diagnosis #Signs
Summary of Pharmacology for Select Proposed COVID-19 Treatments

#Pharmacology #Dosing #Table #COVID19 #Coronavirus #SARSCOV2 #Medications #JAMA
Summary of Pharmacology ... Select Proposed COVID ... -19 Treatments ... #Pharmacology ... #Coronavirus #SARSCOV2
Simplified Representation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Viral Lifecycle and Potential Drug Targets

#Therapeutic
Acute Respiratory Syndrome ... Therapeutic #Targets #Pharmacology ... #SARSCOV2 #Coronavirus ... #COVID19 #JAMA
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Siltuximab) in COVID19 ... Cytokine Activation Syndrome ... correlate with severe COVID ... Neutropenia 2-7% Alternative ... #Pharmacology #
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... SSRI Withdrawal Syndrome ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology # ... Psychiatry #Diagnosis #Signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Vomiting Serotonin Syndrome ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology # ... Psychiatry #Diagnosis #Signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... organ damage • Treatment ... : • Pathophysiology ... Low calcium • Treatment
Remdesivir (GS-5734) - manufactured by Gilead Sciences
Remdesivir blocks the replication of viruses by inserting into the
#Remdesivir #Pharmacology ... #Pathophysiology ... #COVID19 #SARSCOV2