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diagnosis hematology leukemia syndrome acromegaly chronic classification cll differentiation dress endocrinology hodgkins lymphocytic lymphoma mds myelodysplasia myelodysplastic treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... : Blast crises ... smear: Blasts APML ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... #management #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Exam/Signs: • Lymphadenopathy ... • Richter’s Syndrome ... Transform to DLBCL, PML ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology ... #oncology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
organ involvement, lymphadenopathy ... Edema in 70% of cases ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
malignancy Pathophysiology ... Differential Diagnosis ... Beckwith Wiedemann syndrome ... Diagnosis and Workup ... or refractory cases
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Presentation: • Lymphadenopathy ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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