10 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... affecting the lungs ... (NTM) • Fungal ... • Lymphoma • Lung ... • Progressive lung
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
component of many fungi ... infection (IFI) ... surfaces - Infections ... admin of mold-active ... closely related fungi
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... affecting the lungs ... (NTM) • Fungal ... • Lymphoma • Lung ... • Progressive lung
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Differential Diagnosis Algorithm ... GI, lung, skin), ... eosinophilia) • Infectious ... ascariasis), Scabies, Fungi ... Differential #Diagnosis #Algorithm
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... Double-stranded RNA • Fungi ... vasculature via: • Active ... Rigors #Bacteremia #Pathophysiology ... #InfectiousDiseases
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain and Lung ... ) • Fungi: Aspergillus ... febrilepodcast #Brain #Lung ... #Infections #Concurrent ... Diagnosis #causes #infectiousdiseases
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain and Lung ... ) • Fungi: Aspergillus ... febrilepodcast #Brain #Lung ... #Infections #Concurrent ... Diagnosis #causes #infectiousdiseases
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
component of many fungi ... surfaces, Albumin, Infections ... concurrent admin mold-active ... result in + as long ... closely related fungi
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
bacteria, viruses, fungi ... helper T cells and activate ... Complement: Abs activate ... Memory B cells are long-lived ... Humoral #Immunity #pathophysiology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Aspergillosis Pathophysiology ... change in the lungs ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases ... #Fungal #Diagnosis