9 results
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... Metabolic acidosis ... D-lactate (short bowel syndrome ... MDaniyalHashmi1 #AcidBase ... ABG #bloodgas #Acid
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
Aka pyroglutamic acidosis ... Inborn errors of metabolism ... oxoprolinase • Acquired ... screen Treatment ... diagnosis #management #treatment
Acquired Disorders of Reduced Bone Strength: Pathogenesis
 • Hyperparathyroidism
 • Vitamin D deficiency
 • Malabsorption syndromes
Acquired Disorders ... Malabsorption syndromes ... • Chronic metabolic ... acidosis • Physical ... #BoneStrength #pathophysiology
Metabolic Pathways of Toxic Alcohols 

Panel A shows the metabolic pathways of toxic alcohols. Alcohol dehydrogenase
Metabolic Pathways ... Panel A shows the metabolic ... high anion-gap acidosis ... #Pathophysiology ... #Toxicology #ToxicAlcohols
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... mobilizes fatty acids ... produce Acetoacetic acid ... The metabolism of ... for Refeeding Syndrome
Differential Diagnosis of Respiratory Acid-Base Disorders
Alkalosis
A. Central nervous system stimulation: Pain, Anxiety, psychosis, Fever, Cerebrovascular accident,
of Respiratory Acid-Base ... Recovery from metabolic ... acidosis Acidosis ... respiratory distress syndrome ... #respiratory #acidbase
#ICUCard
RENAL
GFR
90-131
mL/min
((140-age)*Wt)/(72*Cr)
Glomerular Filtration Rate (Cockcroft)
CI Cr
90-131
mL/min
(CrU * volume)/CrS
Creatinine Clearance
FENa
0.0-1.0
%
((U/P Na)/(U/P Cr))*100
Fractional Excretion of Na+
Na req
mEq
(125-Na)*0.6*Wt
Required Sodium
FE Urea
(HCO3d-HCO3m) Metabolic ... Acidosis ІнСО3 ... HCO3)+8 (+-2)| Metabolic ... 9 Respiratory Acidosis ... Distress Syndrome
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypomagnesemia • Metabolic ... Hypochloremic metabolic ... Renal tubular acidosis ... Rhabdomyolysis Treatment ... nephrology #management #pathophysiology
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
• Boerhaave syndrome ... Vomiting may lead to metabolic ... abuse may lead to metabolic ... acidosis (loss ... Complications #pathophysiology