8 results
Hyperaldosteronism Testing Algorithm
INDICATIONS FOR TESTING:
Suspicion of primary aldosteronism - Manifestations: hypertension, hypokalemia, metabolic alkalosis
ORDER: Aldosterone/Renin Activity
Hyperaldosteronism Testing Algorithm ... hypertension, hypokalemia ... , metabolic alkalosis ... Hyperaldosteronism #Algorithm ... #endocrinology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Algorithm Acidosis ... Periodic paralysis Alkalosis ... Metabolic alkalosis ... Diagnosis #Causes #Workup
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and metabolic alkalosis ... renal bruit or signs ... Vasculitis • Endocrinologic ... Cushing's syndrome, Acromegaly
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... - Giantism or acromegaly ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Hypogonad (50%) • Metabolic ... malignancy Pathophysiology ... Diagnosis and Workup ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
To prevent hypokalemia ... Due to neuronal metabolism ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Endocrine and metabolic ... Cataracts Labs: Hypokalemia ... alkalosis (Due ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
alkalosis (loss ... abuse may lead to metabolic ... ) • Overall: hypokalemia ... Complications #pathophysiology ... #diagnosis #signs