10 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... → Hypokalemia Metabolic ... #Syndrome #Pathophysiology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Hypomagnesemia - Metabolic ... excretion of Cl > 0.5% Clinical ... #Syndrome #Diagnosis ... #Workup #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... tubule (DCT) Clinical ... Hypochloremic metabolic ... #nephrology #management ... #pathophysiology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... hypokalemia and metabolic ... 109 mm Hg) with clinical ... Vasculitis • Endocrinologic ... Neurologic disorders
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... dissipation of metabolic ... • Serotonin syndrome ... Phaeochromocytoma Neurologic ... Diagnosis #Management #Workup
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... Hypogonad (50%) • Metabolic ... Beckwith Wiedemann syndrome ... Diagnosis and Workup ... Diagnosis #Management #Endocrinology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... may precede the neurologic ... Etiology: • Pathophysiology ... Drug toxicity, Metabolic ... diagnosis #management #neurology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Stiff Person Syndrome ... Pathophysiology ... Clinical Manifestations ... antibody that works ... Management #treatment #neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Nephrolithiasis • Metabolic ... Hyophosphatasia #hepatology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Pathophysiology: ... Diagnosis (Clinical ... #Hepatorenal #Syndrome ... #Hepatology #Nephrology