20 results
Bilirubin Metabolism - Pathophysiology
 • Conjugated Bilirubin
 • Unconjugated Bilirubin

By Dr. Khushboo Gala @LouLectures

#Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... - Pathophysiology ... • Conjugated Bilirubin ... #Metabolism #Pathophysiology ... #hepatology #Liver
Biochemistry and Metabolism of Bilirubin
Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
Biochemistry and Metabolism ... "indirect bilirubin ... #Biochemistry #Metabolism ... #pathophysiology ... #hepatology
Bilirubin metabolism and pathophysiology of jaundice 

#Bilirubin #metabolism #pathophysiology #jaundice #hepatology
Bilirubin metabolism ... and pathophysiology ... of jaundice #Bilirubin ... #metabolism #pathophysiology ... #jaundice #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Phosphatase and Bilirubin ... Metabolism AST ... metabolism: • ... Tests #Laboratory #Metabolism ... #Hepatology #Pathophysiology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Increased Unconjugated Bilirubin ... Disorder • RBC Metabolism ... Classification #Approach #Differential ... Algorithm #Causes #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... postpartum): • Initial symptoms ... infiltration) Differential ... Liver #Pregnancy #hepatology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... slightly elevated • Bilirubin ... bile ducts Differential ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Shock liver • Metabolic ... week • Direct bilirubin ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology