10 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... fibers Spectrum of Clinical ... #signs #symptoms ... #endocrinology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... decreased reflexes Pathophysiology ... damage - CXR should
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Pathogenesis and Clinical ... Due to neuronal metabolism ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Median Nerve Tension Test (Upper-Limb Neurodynamic Tests, ULNT1)

To assess for Median Nerve Peripheral Neuropathy

Shoulder abduction →
positive with symptom ... #ULNT1 #ULTT1 #clinical ... #video #physicalexam ... #sports #msk #orthopedics ... #neurology #ULNT
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
Pathogenesis and clinical ... are uncommon and should ... #Varicocele #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
when evaluation should ... hypokalemia and metabolic ... 109 mm Hg) with clinical ... renal bruit or signs ... Vasculitis • Endocrinologic
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Neurological symptoms ... Drug toxicity, Metabolic ... count in the CSF should
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... • Bilateral signs ... and/or symptoms ... diagnosis #management #neurology
Rickets and Osteomalacia: Pathogenesis and Clinical Findings
 • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
Pathogenesis and Clinical ... Abnormal Vitamin D Metabolism ... #Osteomalacia #pathophysiology ... #diagnosis #signs ... #symptoms