24 results
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
of Diabetic Ketoacidosis ... relative insulin deficiency ... of carbohydrate metabolism ... state and fat metabolism ... #Endocrinology
Rachitic Rosary of Rickets on Physical Exam

Bead-like prominences of bone are seen at the costochondral joints.
#PhysicalExam #clinical ... #video #chest # ... Ribs #VitaminD # ... deficiency #endocrinology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
from hormonal and metabolic ... may cause severe clinical ... Poorly controlled diabetes ... #Differential #Diagnosis ... #Pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... : • T4 deficiency ... mitochondrial oxidative metabolism ... fibers Spectrum of Clinical ... signs #symptoms #endocrinology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
bodies are a normal metabolic ... fatty acid (FA) metabolism ... • Diabetic ketoacidosis ... #differential #diagnosis ... #management #endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... Definition of EuDKA • Metabolic ... level < 200 mg/dL Pathophysiology ... Ketoacidosis #EuDKA #diagnosis ... #management #endocrinology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
C Deficiency) - ... Diagnosis and Management ... poor nutrition Clinical ... C deficiency can ... #Pathophysiology
Acquired Disorders of Reduced Bone Strength: Pathogenesis
 • Hyperparathyroidism
 • Vitamin D deficiency
 • Malabsorption syndromes
Hyperparathyroidism • Vitamin ... D deficiency ... syndromes • Chronic metabolic ... • Smoking • Diabetes ... #differential #diagnosis
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... Pathogenesis and Clinical ... Due to neuronal metabolism ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Vitamin C deficiency ... collection with EDTA Pathophysiology ... Nephrolithiasis • Metabolic