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management differential hematology abnormal aflp algorithm alkaline alp biliary causes cholangitis cirrhosis complications enzymes erythematosus failure fatty feedbackloop gastrointestinal gh
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... postpartum): • Initial symptoms ... #Pregnancy #hepatology
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
liver failure ... abnormalities Liver ... : Loss of metabolic ... #Signs #Symptoms ... #Diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... Pancreatitis - Elevated Liver ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... cycle found in the liver ... Diagnosis of MALA ... gastrointestinal distress and acute ... also includes symptoms
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone: • Liver ... activates lipolysis Signs ... /Symptoms: • GH ... thickness) - metabolic ... #pathophysiology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... /signs should be ... The presence of metabolic ... Areas of diagnostic ... Abnormal #Algorithm #Hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - ACS, AKI, acute ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... or higher • Liver ... #workup #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... symptoms can mimic ... presents as an acute ... lymph node, or liver ... management #treatment #hematology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
- Differential Diagnosis ... • Labs: - Metabolic ... Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness
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