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diagnosis differential causes management symptoms acromegaly algorithm alkaline alp anesthesia anesthesiology anorexianervosa biliary checklist chloride cholangitis cirrhosis complications diabetes diabeticketoacidosis
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... hypertension and signs ... hypokalemia and metabolic ... renal bruit or signs ... Vasculitis • Endocrinologic
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Excessive vomiting - Metabolic ... - Gitelman SIGNS ... increase may cause metabolic ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Due to neuronal metabolism ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... cholangitis #diagnosis #workup ... #hepatology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Radiation • Metabolic ... Lack of UMN/LMN signs ... Hypothyroid • Metabolic ... dystrophies Work ... Differential #Diagnosis #neurology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Hypogonad (50%) • Metabolic ... malignancy Pathophysiology ... Diagnosis and Workup ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
dissipation of metabolic ... hyperthermia crisis (late sign ... Phaeochromocytoma Neurologic ... Diagnosis #Management #Workup
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Nephrolithiasis • Metabolic ... Hyophosphatasia #hepatology
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