343 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... includes symptoms of metabolic
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Definition of EuDKA • Metabolic ... acidosis with pH ... level < 200 mg/dL Pathophysiology ... Ketoacidosis #EuDKA #diagnosis
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
• Incr Glucose Metabolism ... Syndrome - Metabolic ... Acidosis • Shift ... Refeeding #Syndrome #diagnosis ... #pathophysiology
Acquired Disorders of Reduced Bone Strength: Pathogenesis
 • Hyperparathyroidism
 • Vitamin D deficiency
 • Malabsorption syndromes
syndromes • Chronic metabolic ... acidosis • Physical ... #BoneStrength #pathophysiology ... #differential #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypomagnesemia • Metabolic ... Hypochloremic metabolic ... Renal tubular acidosis ... Gitelman #Syndrome #diagnosis ... nephrology #management #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
- Differential Diagnosis ... • Labs: - Metabolic ... acidosis - Rhabdomyolysis ... Collapse: • Pathophysiology ... - Mild lactic acidosis
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Inborn Errors of Metabolism ... additions, for diagnosing ... acute metabolic ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #InbornErrors #Metabolism
Simplified Diagnosis of Metabolic Disorders
#Diagnosis #Peds #Pediatrics #Inherited #Congenital #Metabolism #Metabolic #Diseases #Disorders #Ketones #Ammonia #Differential
Simplified Diagnosis ... of Metabolic Disorders ... #Diagnosis #Peds ... Inherited #Congenital #Metabolism ... #Metabolic #Diseases
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
Vomiting may lead to metabolic ... abuse may lead to metabolic ... acidosis (loss ... Complications #pathophysiology ... #diagnosis #signs
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
High Anion Gap Metabolic ... Acidosis (HAGMA ... - Differential Diagnosis ... during hypoxic metabolism ... #Anion #Gap #Metabolic