49 results
Ethylene Glycol Toxicity

#Pathophysiology #Toxicology #EthyleneGlycol #Metabolism #Fomepizole
Glycol Toxicity #Pathophysiology ... #Toxicology #EthyleneGlycol ... #Metabolism #Fomepizole
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... includes symptoms of metabolic ... LacticAcidosis #Toxicity #Toxicology
Toxic Alcohol Ingestion
Alcoholic ketoacidosis - Methanol - Ethylene glycol - Isopropyl Alcohol
 • Metabolic Acidosis
 •
Isopropyl Alcohol • Metabolic ... Ingestion #diagnosis #toxicology ... #comparison #table
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
people variably metabolize ... into its active metabolite ... codeine ultra-rapid metabolism ... activity as the M1 metabolite ... in poor codeine metabolism
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC Pharmacology ... Bioavailability - Metabolism ... Warfarin #DOAC #Pharmacology ... #NOAC #comparison
Salicylate metabolism.
#Pathophysiology #Metabolism #Toxicology #Salicylate #Aspirin
Salicylate metabolism ... #Pathophysiology ... #Metabolism #Toxicology
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Serotonin Syndrome Drug ... Precipitants and Pharmacology ... Lithium ↓ Serotonin Metabolism ... Serotonin #Syndrome #Pharmacology ... differential #diagnosis #drug
Toxic Alcohol Metabolism and Metabolites

#Toxic #Alcohol #Metabolism #Metabolites #Toxicology #Pharmacology
Toxic Alcohol Metabolism ... Toxic #Alcohol #Metabolism ... #Metabolites #Toxicology ... #Pharmacology
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
Acetaminophen metabolism ... Acetaminophen #APAP #metabolism ... #toxicity #Toxicology ... #Pathophysiology
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Y t amino acid metabolism ... Starvation (↑ muscle catabolism ... (direct ↑) Drugs ... Differential #Diagnosis #Pathophysiology