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Pharmacotherapy for Migraine Prophylaxis 

Who is indicated for migraine prophylaxis? Patients who experience more than 3
Prophylaxis ... prophylaxis? ... headaches per month ... appropriate acute treatment ... Pharmacology #Management #Neurology
Acute Treatment of Migraine

- BWH Medicine Chiefs @BrighamChiefs

#Migraine #Treatment #management #neurology #headache #medications
Acute Treatment ... of Migraine - ... BrighamChiefs #Migraine ... #Treatment #management ... #neurology #headache
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
• In migraines ... : • Migraine: ... with aura > migraine ... > episodic migraine ... ophthalmology #Neurology
Migraine Treatment Overview

 • What is a Migraine?
 • Pathophysiology
 • Common Migraine Triggers
 • Diagnosis
Migraine Treatment ... • Pathophysiology ... • Common Migraine ... #pharmacology #prophylaxis ... #neurology
Migraine Prevention and Prophylaxis
Who to Consider: 
 • ≥ 4 significant headaches or migraine attacks/month
 •
Migraine Prevention ... and Prophylaxis ... treatments • ... #treatment #prevention ... #prophylaxis #neurology
Drugs Useful in the Treatment and Prophylaxis of Migraine Headaches
Several classes of drugs are effective in
Useful in the Treatment ... and Prophylaxis ... of Migraine Headaches ... #Migraine #Headache ... #Treatment #Prophylaxis
Causes of Primary Headaches - Differential Diagnosis Algorithm
Unilateral
 • Migraine (Throbbing/Pulsating)
Bilateral
 • Tension/Stress Headache (Tightening, Band-Like,
Causes of Primary Headaches ... Unilateral • Migraine ... Tension/Stress Headache ... • Cluster Headache ... #Neurology #Differential
POUND Mnemonic for Diagnosis of Migraine Headache
P Is the headache Pulsatile in quality?
O Is the duration
for Diagnosis of Migraine ... Headache P Is ... the headache Pulsatile ... features LR 0.41 #Migraine ... #PrimaryCare #Neurology
Migraine - Preventative Treatments

 • Anticonvulsants: *Topiramate, *Sodium valproate, Gabapentin, Pregabalin
 • Antidepressants: Amitriptyline, Venlafaxine, Duloxetine,
Migraine - Preventative ... Treatments ... neudrawlogy #Migraine ... #management #prophylaxis ... #pharmacology #neurology
Prophylactic Migraine Medications

Established Efficacy: 
 • Metoprolol, Propranolol, Timolol, Divalproex, Valproate, Topiramate, Frovatriptan
Probably Effective: 
 •
Prophylactic Migraine ... Cyproheptadine #Migraine ... #prophylaxis #Medications ... pharmacology #EBM #neurology