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diagnosis secondary insufficiency management psychiatry causes complications differential hyperplasia hyperthyroidism syndrome urology 21hydroxylasedeficiency 21ohd addisons alkaline alp anorexianervosa anxiety behavioraldisorder
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
- Pathophysiology ... Primary AI = adrenal ... Secondary AI = the pituitary ... Insufficiency #Pathophysiology ... #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... and Symptoms • ... • Hypothalamic–Pituitary ... pressure • Glucose Metabolism ... #endocrinology
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... vomiting • Fatigue Signs ... Reduced libido • Signs ... addisons #disease #endocrinology ... #diagnosis #signs
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... thickness) - metabolic ... #pathophysiology ... #pituitary
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Phosphate Physical Symptoms ... : Commonly no signs ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-OHD in the adrenal ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
Management Summary Primary ... ketoconazole, etomidate) Symptoms ... pan-hypopituitarism including: pituitary ... Insufficiency #Primary ... Diagnosis #Management #Endocrinology
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